From Rome, is it better to fly to Bari or Brindisi to start a tour of Publia in Lecce?
You have lots of answers on your other thread.
https://community.ricksteves.com/travel-forum/tours/fly-to-bari-or-brindisi-to-tour-puglia
But since you have now mentioned starting in Lecce, I will add that Brindisi is closer.