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Florence on a Sunday

I will be in Florence for a few days at the beginning of October and I would like to tour the countryside and check out some wineries on Sunday. Maybe even visit Siena... However I have been reading that so much closes on Sunday, does anyone know if wineries are in fact open? And are there any winery recommendations? Do we need to make reservations or can we stop in? Is it similar to Napa Valley?

Thanks!