Hi, Michelle! Are you flying into Marco Polo airport, then staying in Venice for your first stop?
If the answer is yes, you have a few options--
Cheapest: Take the ATVO bus. You can take a shuttle directly to the Piazzale Roma in Venice, then walk or take a vaporetto to your hotel from there.
If you find it better fits your schedule, you can shuttle from the airport to the Mestre Station on the mainland, then hop on the train for the short ride to Stazione di Venezia Santa Lucia (the station in Venice proper) This is particularly useful if you are staying in Canareggio or Dorsoduro. And even though it's a 2 step process, it's quite easy, it will cost less than €11 and the whole trip will probably be 30-45 minutes, depending on connections
ATVO- http://www.atvo.it/en-venice-airport.html
Trenitalia- https://www.trenitalia.com/en.html
Not as cheap, but may take you closer to your hotel if your bags are heavy: Water shuttles. Depending on where you're staying, this might be a good choice
Alilaguna- https://www.alilaguna.it/en/lines/linea-arancio/orario
I used all of these methods in the 1990s. If someone has recent taxicab info, it may be worth comparing. Back then, cabs into Venice were crazy expensive & I never got in the habit of using them, but maybe the fare has changed.
EDITED TO ADD that the hotel where you're staying is convenient to both Piazzale Roma and Stazione di Venezia Santa Lucia, so either the bus or the bus/train are good bets.