First night in Rome to depart to Orvieto

Hotel Sonya is very nice, walking distance to Termini
https://www.hotelsonya.it/en/

I would second Sonya -- about three blocks from Termini across from the Opera House. Great breakfast and lattes. Several good restaurants in the area depending on what you want. For quick one night stays we sometimes use Hotel Contila. Just one block south out the side door of Termini. Very convenient but breakfast is very so so. Aberdeen is an excellent hotel but five or six blocks from Termini. The Target restaurant behind Aberdeen is very nice with limited outdoor seating.

From FCO there are trains to Orvieto without going into Rome, just an FYI incase you did not know. One night only in Rome sounds like a lot of dragging luggage around to me. J

There are no direct trains from FCO to Orvieto
All Change in Tiburtina or Termini

Christine is correct. I don't see any problem with an overnight in Rome. We had frequently done that as it provides an opportunity to relax and adjust to jet lag.

I have gone from FCO to Orvieto without going into Rome, the train went North from the airport. There was two rail lines at the airport one that went north and one that went into Rome, however things may have changed. It was all the back in 2005. J

The airport FCO website still shows a north bound train, and there is now 3 lines. J

I’m not sure what you are seeing.
Trenitalia is the train company and there are no trains to Orvieto from FCO that don’t change in Tiburtina or Termini.

We were just there and traveled from Rome to Orvieto after a 1 night stay in Rome
In all my planning I never saw a train to Orvieto direct from FCO.

https://www.trenitalia.com/content/tcom/en.html

Thanks, all. I think we like the idea of the first night in Rome, anyway - begin to become adjusted after our trip over from Atlanta and up early to catch the train to Orvieto.