My husband and I are going to be in Italy this year for Easter Week (not purposefully, it just worked out that way after a business trip). We are currently planning to fly into Florence, spend 3 nights in Florence or Siena, then rent a car and do some hill towns (picking a home base from RS's suggestions) for 3 nights, then go to Rome for the final 3 nights -- which are, as it turns out, Maunday Thursday, Good Friday and Holy Saturday.
It seems like everything is open those days (Sunday/Monday being the holiday closures).
I suppose my big question is what do we need to book far in advance, given that I expect there will be A LOT of people in Rome -- also, will Rome be totally over run and crazy to do anything (even the non-religious stuff)? I know 3 days is already not enough to see everything -- would it be better to save it for a different trip and pick a third city in Tuscany/Umbria?
All opinions welcome :)