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Driving from Cinque Terre to Amalfi

We are planning to drive the Autostrada (wherever possible) from Cinque Terre to the Amalfi area, but feel it may be too much driving for one day. We're looking for a recommendation of a town to stay overnight, just before or past Rome to break up the trip. (We are going back to Rome at the end of the trip.) We plan to stop in Siena for lunch and a quick (second) visit but this too close to stay overnight. Any suggestions/recommendations?

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The Civitavecchia area, if you just want an overnight stop on the A12 that is about half way between CT and Amalfi; it is northwest of Rome on the A12.