Hi, I’m wondering if Montepulciano would make a good hub for a few nights to do day trips. We have been to Florence and Siena.
Thanks,
Pienza's old town is worth visiting.
Providing you have a car, and know how to avoid the ZTLs. Montalcino, Cortona, and Arezzo are less than an hour away. Orvieto is just over an hour's drive.
The drive between Montepulciano and Montalcino with a stop in Pienza is lovely.
In 2019 we stayed 3 nights near Montepulciano. Our trip report describes our day trips and might be useful reference (part 6): https://community.ricksteves.com/travel-forum/trip-reports/italy-2019-sicily-sorrento-amalfi-pompeii-rome-orvieto-tuscany-siena-florence-cinque-terre-milan