I just wanted to share this for those who are booking a car. We booked from Rome so we could drive around Tuscany for two days before going on to Cinque. We were thinking we would drop off in Florence but thanks to some great advice I received from others on this forum we realized we may just drive to La Spezia to drop off and take the train to Cinque. We booked online with www.autoeurope.com. During the process we called them twice to discuss where to drop in Florence then later when we decided on La Spezia and they were excellent to speak with!
Then came the best part. We had originally searched for a two day rental picking up at 9am on a Sunday and dropping off by 9 am on Tuesday but with the La Spezia factor we bumped our drop off time to 10am which pushed up to a 3 day rental and thank god it did. It was $200 less for the 3 day than the 2 day rental with the exact same car!!!!!