I am starting to build an off season trip to Florence, Siena, Assisi, and Bologna. I intended to use Florence as a base, but Assisi is close to a 3 hour train ride. Would an over night in Assisi be the answer? We are not keen on driving, age is becoming a factor, but perhaps, we could do a car rental from Siena to Assisi and back in a day , making Siena a 2-3 day stop. We try to avoid staying one night stops. Any suggestions? Any special knowledge I am missing?
Also, i am open to adding anything to our itinerary that might be an easy train ride. Would it make sense via train Florence to Perugia and spend 2 nights there, short train ride to Assisi?