Best way to Lucca from Rome

the fastest way is Via Florence (train change in Florence). No Pisa involved.

The fastest will be a Freccia train to Florence then a Regionale to Lucca. I didn't look it up, just an educated hunch.

Thanks.. What I thought but always willing to learn.

Check schedules here
www.trenitalia.com
Enter from Roma Termini to Lucca.

The Rome to Florence portion can be done aboard the www.italotreno.it