Tough price point, but in November it is possible. I prefer Prati, near the Vatican and surprisingly convenient with walking, tram, bus and Metro, or the Centro Storico around the Pantheon/Piazza Navona where walking to almost everything is easy and there are excellent bus connections as well.
The problem with the Termini area is that it is the Termini area, with little charm and currently -- through Dec 7 -- in the midst of huge street projects in preparation for the Jubilee, which starts Dec. 8.
I did a search on VRBO.com for a random week in November and found several Prati apartments for less than Euro 150 per night. An apartment is a great idea when you are 4 people for so many nights. More space, a chance to cook light meals, keep sbacks around. And if it is central like Prati or the Pantheon area, easy to return to for a brief rest between events/tours.