Congrats on your upcoming trip to Italy! Can’t think of a better way to celebrate a birthday. In fact, I landed in Rome on my birthday this year, and enjoyed a fantastic tour of the Campo de’ Fiori, Jewish Ghetto, and Trastevere neighborhoods right after landing. Jet lagged and had so much fun!
All of my trips to Italy have been as a solo female traveler. Comments on Rome and Florence below.
Rome
First visit: Rented an apartment in the Monti neighborhood. Most of my sightseeing activities were close to this neighborhood, and I loved the vibe. Plus, my apartment was right around the corner from Fatamorgana gelato, which became a daily treat. If staying in this neighborhood, try to pick a place that’s not on one of the main streets as that will be noisier.
Second visit: Stayed at Albergo Santa Chiara, one block south of the Pantheon and across the street from Santa Maria Sopra Minerva. I can’t recommend this hotel enough! On my first trip to Rome, I met 3 retired ladies who have known each other and traveled together the last 40 years. They always stay here. It’s pricier due to location, but totally worth it. I requested a quiet, interior room, and my room was just right.
Third visit: Albergo Santa Chiara for part of the trip, then Hotel Aberdeen for the last night before flying home. Other forum members like this hotel. I have nothing against it, per se, but my room was even tinier than at Albergo Santa Chiara and was very hot and stuff (in March). Also, I agree with Roberto about the Termini area. I am not inclined to stay in that area again.
For Rome, look for lodging that is central to most of the sites you want to see. It’s well worth it.
Florence
First visit: Hotel dei Macchiaioli based on the write-up in Rick Steves’ Florence guidebook. A great place to stay for a first visit to Florence because it’s on Via Cavour, which is the street that you take south that deposits you right in front of the Duomo. Major Stendhal Syndrome! The hotel was quiet, and the staff all quite lovely.
Second visit: Palazzo Guadagni based on a recommendation on the Girl in Florence site. This hotel is in Piazza Santo Spirito. My room was on the top floor and faced Palazzo Pitti. Loved staying here as the Oltrarno district is much less touristy. Will likely stay here the next time I am in Florence.
Please let me know if I can help with any additional female solo traveler in Italy questions and happy planning!