Are there any current Covid restrictions

Honestly Google is your friend. Took a few seconds to type in Rome Travel restrictions.

Here’s the answer: https://it.usembassy.gov/covid-19-information/

Sherpa was the 'go to' resource even for airlines and tours for a lot of the pandemic https://apply.joinsherpa.com/map?affiliateId=sherpa&language=en-US
I found airline websites also provided details.
Bring proper masks, as it may be difficult to know beforehand what countries require mask use for transport, sites or enclosed spaces.

Thanks for your help. I read the airline, US government and Sherpa sites are there are no current restrictions for US citizens.