Apian way

Quite detailed instructions are in the Rick Steves Rome guidebook, depending on if you want to go by bus, Metro and bus, or walk.

Rome is quite large so just asking "from rome" is a bit vague. Where in Rome? Most of the commonly visited part of the Appian Way is within Rome.

You second sentence makes no sense to me.

There is a bike rental facility midway along the commonly visited part of the Appian Way, and others elsewhere in Rome.

You might be interested in the Aquaduct Park.

You can take the bus to the Via Appia Antica (there are several roads that contain the name "Appia"), at the Cecilia Metella stop there is a bar that rents bikes, or you can walk in either direction from there (toward or away from Roma). Acqueduct Park is great.

Getting there is a bit of a challenge. Take the Metro to Circo Massimo or (better) to Pirimide and transfer to bus number 118, which departs every half hour or so. The bus stop is about a block away from the Pirimide Metro exit point.
Easiest way to do it is to just buy a B.I.G. (daily) ticket at a metro ticket office or at one of the kiosks located around the city - they're good for unlimited day travel on metro, bus, and trams. Otherwise you'll need to purchase separate tickets at every transfer point. Also, the BIG is already time stamped when you buy it so you needn't worry about validating it on the bus.
Stay alert for the Appia Antica/Quo Vadis stop, which is about 4 or 5 stops after departing Pirimide. Easy to miss - not well marked. There's a good Information office/park headquarters located immediately in front of you just as you get off the bus. Wasn't signed especially well and we initially walked right past it without realizing it. Started walking down the street marked "Appia Antica" for a few blocks before we realized our error - lots and lots of traffic, to the point of being dangerous for pedestrians. We backtracked to the Info point, purchased the park map (1 Euro), and spoke with the helpful agent who pointed out the correct entrance to the path. They also rent the bikes there which, if you have the time, is an outstanding way to cover the 5-6 miles of road...just need to walk the bikes from the office to the entrance (about a block) to keep from becoming a statistic. Recommend visiting the park website at www.parcoappiaantica.it to familiarize yourself with the layout. The website is in English with a good map provided to help you get your bearings - easy to go off on a tangent unless you know exactly where your going.
Once on the "correct" path it's wonderful. Minimal auto traffic until you pass the entrances to several of the catacombs and the Basilica of San Sebastian, after which there's a two block walk back on the main drag before the old road branches off again to the left. After that it's smooth sailing for about 5 miles on one of the prettiest, and certainly the most historic, pathways you'll ever walk. Hardly any vehicle traffic at all - believe it's restricted to local traffic only, which is minimal.
The 118 bus unfortunately doesn't go all the way to the end point of the preserved section of the Appian Way, so you'll need to make your hike or bike an out and back if you want to catch the 118 for a return trip to the metro station. The park map does show some other bus stops just off the Appian Way, and I'm sure you can Google their routes and probably do the walk only one-way, but we didn't have time to sort it all out.
Bottom line is that it's a terrific day out, but do check out the park website to get your bearings before setting off.