I haven't been since 2017, when I was on a "College Art Museum" package trip. We were staying a quick walk from both exhibition spaces, and had unlimited admission for several days. That allowed us to eat where we wanted, and to return to our rooms if we wanted to rest or freshen up. It was a nice luxury. Sometimes they check photo ID for multi-day tickets, for obvious reasons.
Because we were a group, it turned out to be easy to share the cost of a water taxi for a miserable 7AM or whatever it was, return flight to the eastern US.
You don't say how religious an art-museum type you are, and if you REALLY like Contemporary Art. One reason I raise that is that you might do well to discard the idea that you are going to see "everything'. Some pavillions will have longer lines than you have the time to stand in (check there throughout the day ... ), and the Arsenale can be slow moving inside. Also note that big galleries, auction houses, and art charities will have free-standing shows (often quite large) all over Venice. You might check to what extent this allows you to see the non-public interior of some palace or other, for example. 98% of these are not secret or ticketed, you just have to find the web page or handout that lists them.
It was easy to visit the US Pavillion (Mark Bradford) multiple times, and even a couple of other popular ones. Sometimes it depended on whether the interior was designed as a linear, slow-moving line, or had wider open spaces. There were some artworks (like a big diorama where you had to wait to put your head up through a hole in the center. I don't remember which pavillion.)
Our hotel (Hotel Bucintoro, small, already booked up, I'm sure) meant that we passed Via Giuseppe Garibaldi, which has about 20 restaurants, many of which put out Hi-Top tables when the weather was good. This somtimes afforded a quicker, non-slowfood, lunch, avoiding taking two hours off art-viewing. Air conditioning is important in the summer.
Make sure you save some time for the landmarks of Venice. I would say that it is not absolutely essential to visit Murano, but that's a matter of taste and priorities. Any museum that requires a timed ticket is probably worth it.