Is the American Express card accepted in Rome?
Yes and No... Most vendors do not want to see the AMEX card due to the higher fees. So MC and Visa are much more widely accepted. When living in Rome, I never used my AMEX card because of the additional fees I had to pay for the foreign transactions!
This is one time you can leave home without it. AE is only accepted at higher end hotels and restaurants if at all.
To with a capital one card. very good rates.