I have returned from my incredible two week trip to Italy - Venice, Florence, Cinque Terre, Rome. It was absolutely amazing! I enjoyed every leg of the trip (loved Cinque Terre!) and had no major problems throughout the journey. Unfortunately, when I arrived home, I had a phone message from American Express questioning some charges and it looks like there has been some fraud. I was very careful with my AE card and tried to just use it for hotels and occasional meals. However, it appears that a charge to "Zurich-Connect.imilano" for $1400+ went through and then a few charges to "genertel" were denied on the day I was traveling home.
I think that American Express will straighten it out (card has been cancelled and investigation is in process). I'm not sure what I could have done differently but I thought that I'd send out a warning about what happened.