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Airbnb/vrbo

What neighborhood would be best in Rome? We would stay 4-5 nights, would like to see the main sights, and experience the culture. Do not mind walking but would like the transit accessible as well. Arriving in Rome from the airport. Thanks

Also… guesthouse or working “farm” to stay at in Tuscany?

End of March

Staying off Via Giulia or Via di Coronari is my preference based on walkability and what's aroudn you. If you only need one room I would recommend a hotel. Often times you have to communicate checkin times with apartment rentals in Rome and its a bit of a hassle. Hotels you just check in. That said, if you're traveling with a group its worth the apartment.

Agriturismo in Tuscany is a great way to do things. Look for somethign near San Gimignano or Siena. Beautiful areas.

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I really like the Monti neighborhood. Close to Termini train station, and a reasonable walk to most sights in the city center.

Enjoy your trip.