14 days (15 nights) in Rome

Goodness, you've planned long and hard for this trip.
Have you considered getting reservations to attractions like the Vatican Museum and the Borghese Gallery on specific days. Otherwise, I urge you to keep your trip variable--not planning every minute of every day.

Travel in Italy is not like everywhere. There's so much art, architecture, history, culture and food to take in. You don't need to overdose yourself--but it's best taken slowly or your trip could easily be a blur.
With the days you'll be in Italy, have you thought about taking 4 days of your trip and taking a fast train up to Florence?
We stayed one time at OliveTreeHill.com, which is a great bed and breakfast 20 miles south. There's just about as much in the suburbs to see as there is in the center city. We hiked down 1500' from Castel San Pietro on 3000 year old footpaths to the somewhat restored pagan temple of Palestrina on Easter Sunday. Our host, Ivano, is also a fabulous tourguide.

The mouth of truth could be grouped with your Trastevere sights if you're good walkers. It's also not terribly far from the Forum. You're even closer to the Jewish Ghetto.

David, we will have an early entry reservation for the vatican and you have to book the borghese gallery in advance, we will also book the coliseum, the palazzo valentini as well as the 2 food tours ahead of time (we already paid for these) but those will be the only days with anything booked ahead of time. other than that we will check the weather and gauge our museum tolerance and pick the segment from there.

We have been to Florence and Venice before. We thought about doing this 5 nights florence and 10 Rome but as you can see we will not come close to seeing all we want in Rome in 15 nights, so we can hope for a 3rd europe trip to go back to Florence (which might end up being that day trip I mentioned above)

I would combine Santa Maria del Popolo with the Borghese. While a bit of a walk from the museum, it's still a nice ramble all the way through to the Pincio and a very nice overlook before descending to Piazza Del Popolo and the church. There are also a couple of outdoor cafes in the park for a short rest and a beverage before resuming your walk.

Great church; glad you're trying to include it. That piazza is also historically important so this is a good way to combine multiple attractions.

I don't see the Pantheon or San Giovanni in Laterano on your list? Personal opinion but I think both of them are more important structures than some of the other churches on your list. I would add San Giovanni to your Baths of Caracalla day, and the Pantheon (and Piazza Navona) to your Monti day, maybe.

You probably already know this but if not, see Santa Maria degli Angeli e dei Martiri when you do the Baths of Diocletian. While incorporating part of the ruins, it has its own entrance on Piazza Repubblica.

Oops, I see now that you have more days you can add as you've only listed 10 of 14. Scratch adding the Pantheon to Monti...

I would group the Pantheon, Area Sacra, Piazza Navona, Santa Maria in Sopra Minerva, Capo Di Fiori, Sant'Ignazio and Palazzo Farnese on one additional day.

I agree with previous posters that you will need to make reservations for some of those sights, particularly Borghese. However, it's still too soon to get that time reserved, so you will need to set yourself a reminder to book 6 weeks or so beforehand. On the day you see the Borghese you could see the Capuchin crypt, as it's in the same general area. Also, on the day you see the AppiA Antica you can see the acquedects, as they are in the same general vicinity. There are bicycle tours in this area that also include the catacombs if you are interested in biking.

Sorry i didn't add all of the free sights in the centro (pantheon, and such) we will be seeing all of those (only about 10 minutes from our hotel room). And I got lazy and called st giovanni in laterano as st john's.) I know the places i have to book ahead of time (we saw all of them in 2013, and will get them booked soon (we are about 7 weeks out) Thanks for the grouping suggestions.

You probably have done this, but I always enlarge s good city map and start highlighting the points of interest. A more or less logical path will emerge, concentrate on seeing sections of the city. Castel Sant'Angelo can go at the end of a Trastevere day, for example.

The Keyhole of the Knights of Malta is very near Santa Sabina, which has some of the oldest carved wooden doors and otiginal ironwork on the Windows. There is a garden nearby where locals take their children, with more great views of Roma. You can walk down to the main street across from the Circus Maximus, passing by an extensive rose garden.

Santa Prassede is quite close to Santa Maria Maggiore, and both are not far from San Giovanni in Laterano and San Clemente.

Santa Maria Sopra Minerva, the Pantheon, San Luigi dei Francesi, Ara Pacis, Piazza Navona are all close to Campo de' Fiori.

Kathy's suggestion is very good for the Galleria Borghese, Etruscan Museum, the Pincio, and Piazza del Popolo/Santa Maria del Popolo. Then walk down the Corso to the Vittorio Emanuele II monument for the elevator ride to the roof.

The Case Romane del Celio is very close to the Colosseum and the Church of San Gregorio is in between them. Trajan's Markets are nearby in the other direction. San Pietro in Vincoli is very close as well.

Sounds like my list of favorite places in Roma!

Just a little background. We are in our mid 30's and quite active (we walk close to 15 miles a day when in vegas and do lots of mountain hiking here in montana), we plan on spending at least 12-14 hours a day out (that will include lots of time just sitting at a cafe) We liked the centro much more at night than in the day last time which is part of why you don't see any of the staples (pantheon, spanish steps, trevi (honestly we weren't impressed with either the steps or the trevi), navona and tons of squares that are on most itineraries. We will be walking past them many many times during the day and will spend our nights wandering the city.

(honestly we weren't impressed with either the steps or the trevi)

I know. Makes you wonder what all the fuss is about, eh?

It wasn't clear that you'd been to Rome previously so that info - as well as ability to put serious miles on your shoes - was helpful. You sound like you travel a lot like we do!

We don't travel much (this will be our second overseas trip) but vegas is cheap and we live by glacier National park in Montana so we are good with miles on our shoes. BTW it does say that we had gone before in the original post. We don't make enough to be able to travel to relax, we get to do enough of that at home, when on vacation we like to see things, eat good food and do some people watching. Our original itinerary for this trip was much more laid back, almost too much so. So with this one we are going to plan more than we can actually do each day and then order it in the most important to us to the least and then when we get tired of sightseeing for that day we will just stop. Our hotel does have a beautiful roof top terrace (hotel campo de fiori) so maybe we will go aginst our usual and spend some time up there relaxing.

anyone else have any suggestions?

After 4 1/2 years of living in Rome, we still did not "finish." Don't be frustrated if you miss something. By leaving some sites and sights out, you can add in time to just wander. There is a wonderful book called "24 Great Walks in Rome" that can guide your steps between monuments and museums.

I see you have Galleria/Palazzo Colonna on your list. Just want to be sure you know it is only open on Saturday mornings.

Laurel, thanks. we plan on leaving much of this out. Also thanks for the book recommendation I will check that out. We did know about the colonna thing only being open on weekends but it would be smart of me to write that down lol.