So, my spouse had a biz trip to Milan, and we had to plan a very quick trip around it. Here's what I came up with, any comments or suggestions? Its pretty packed, I tried to roughly follow the Rick Steves itinerary from his tour (which was unfortunately sold out). Hopefully I didn't screw anything up. All hotels are central, plan is to use taxi's and high speed rail to get around. This trip is just a taste, hopefully we can come back in a few years to do it justice...
Day 1- arrive Milan, hotel
Day 2 - 6 hour "milan in one day" tour with Veditalia
Day 3 - Check out hotel early, fast train to Venice arriving at 10:40. Drop bags off at hotel and catch walks of italy 2pm tour of st marks, doges
Day 4 - Unscheduled day, Vaporetto tour, or perhaps secret venice walking tour? or just mosey around
Day 5- AM fast train to Florence, arrive 1:30. Drop bags in hotel, visit Duomo in afternoon. Climb dome at 4pm before sunset
Day 6 - full day Florence in a Day tour with David/Academia, Uffizi, walking tour
Day 7 late am fast train to Rome - Unscheduled chill, then Welcome to Rome twilight walking tour (free, from italiapass?)
Day 8 - Colosseum underground VIP tour (Through Eternity)
Day 9 - Borghese gallery AM, maybe Through Eternity Secret Rome tour in PM?
Day 10 - Pristine Sistine tour (Walks of Italy)
Day 11- FCO airport