Logding in Dublin: Which neighborhood best for hotel

There are 3-4 neighborhoods in central Dublin from where you can easily walk to most of Dublin’s attractions. The one north of the Liffey River along O’Connell Street is called “North City.” Here you’ll find Dublin’s main shopping street and the historic General Post Office along with many hotels. South of the Liffey River is the famous entertainment district called the “Temple Bar” with its theaters, pubs and restaurants. Just west of the Temple Bar neighborhood is a more residential neighborhood with small grocery stores and cafes called “The Liberties.” I stayed at the “Staycity Aparthotel Tivoli” at 135 Francis Street and found it handy to walk everywhere on the itinerary for a 5-day stay. There also are Staycity Aparthotels near Dublin Castle and Trinity College which brings us to the fourth neighborhood next to the Temple Bar where you can find many of Dublin’s finer hotels along with the pedestrianized shopping of Grafton Street. Grafton Street links Trinity College with one of Dublin’s most beautiful parks, St.Stephen’s Green. This is the “Trinity” neighborhood where you’re near the must-see National Gallery of Ireland which is on Merrion Square, and the must-see National Museum of Ireland which holds golden archaeological treasures created during thousands of years by the Celtic people who are the ancestors of the Irish.
All these neighborhoods are central and considered safe for visitors.

I stayed at Buswell's Hotel on Molesworth Street in the "Trinity" neighborhood as described above, right across the street from the National Archeology Museum, and easy walks to St. Stephen's Green, Grafton Street, and Trinity College. Central Dublin is pretty compact and all the neighborhoods described are in walking distance of each other, and certainly safe. I'd stay away from Temple Bar for lodging because it's a noisy area in the evenings (not unsafe though).

Thank you!

Some excellent suggestions from the others. My only caution is that the areas around Trinity College and Temple Bar can be pretty noisy in the evenings until very late at night. Most Dublin hotels don't have A/C so you may need to open your windows ... inviting all the racket into your room just as you're trying to get to sleep.
Suggest getting yourselves some good soft earplugs to cancel out the noise, or consider staying in a quieter neighborhood a little further afield. We usually stay down in Ballsbridge for that reason, but anywhere along the DART line would allow you to zip into the city center but then leave the congestion behind you once you've finished touring for the day.