Bus or taxi from Heraklion airport to Heraklion

I don't think we can give good advice on such limited information. I think it would depend on whether you are coming in with big suitcases, to check into a hotel. How heavy is your luggage? How far from the port area (where the local bus stops) is your hotel? What time of day? Do you mind a short wait for t he bus? If you want to economize, you might take a bus to the in-town bus station then pick up a taxi for a short ride to hotel.