Reformation Cities Tour

I just googled "reformation tour europe" and got lots of results for guided tours. I'd use their itineraries for planning the route and number of days. I would not try to duplicate a guided tour itinerary as you usually need more time on a DIY schedule. Once you have your travel plan, folks here can help with hotel and food recommendations.

I agree with Chani, but if you are planning for the big 500th next year, get your hotel reservations in order sooner rather than later. Don't forget Erfurt.

Thanks for the help. We are going this year to avoid next year's crowds.

You may enjoy some articles such as this one on Erfurt and other tidbits that you can find by searching above for either Luther or Reformation on this site. Rick's Germany guidebook covers practical details for visiting Erfurt, Wittenberg, Wartburg Castle, Leipzig, and more. In Prague, you can remember Jan Hus at a reconstruction of the chapel where he preached. Rick doesn't have any material on Geneva.

"Erfurt, Wittenberg, Wartburg Castle"

You may want to visit Augsburg in bavarian Swabia, too, the place of Luthers examination by cardinal Cajetan in 1518 and the place of the Confessio Augustana of 1530 (on the historical background see https://en.wikipedia.org/wiki/Diet_of_Augsburg, on St. Anna, Luthers home during his visit to Augsburg see https://en.wikipedia.org/wiki/St._Anne%27s_Church,_Augsburg). Augsburg would be a convenient intermediate stop on your way from eastern Germany to Switzerland (it has several other attractions as well, e.g. Elias Holl's magnificent renaissance town hall).

Another place on your way to Sitzerland with reformation context is Lindau at (rather: in) Lake constance, a beautiful little old town within lovely landscape.

Upcoming events in the context of the reformation jubilee are listed at https://r2017.org/en/worldwide.

Enjoy your trip!

.. And before Augsburg you may want to visit Nuremberg, the first free imperial citiy to introduce the lutheran creed in southern Germany, setting an example that was followed by many other imperial cities in today's Bavaria (e.g., Rothenburg o.d.T., Windsheim, Weissenburg, Memmingen, Lindau). There is a website dedicated to the reformation in Nürnberg: http://www.luther2017.de/en/news/nuernberg-stadt-der-reformation/ (also in English).

If you base yourself somewhere in what Rick Steves calls "Luther land" you can see many places related to the Protestant Reformation, especially if you rent a car. And not just the obvious places like Wittenberg, Wartburg castle or Erfurt. There is also Torgau, a nice preserved town with a huge castle where you can see the first Protestant church and the tomb of Luthers wife. Mühlhausen/Thüringen was not just the capital of Thomas Müntzers anabaptists, it's also a mostly preserved town with a town wall. Nearby is Bad Frankenhausen, where a huge panorama remembers the Peasant's War. It was commissioned by the East German Commies, but the artist Werner Tübke didn't deliver Socialist Realism but a deeply pessimistic mix of the German Middle Ages and Italian Renaissance.
You could also visit Schmalkalden near Wartburg castle. Schmalkalden is a small town with a nice centre full of half-timbered houses and a big castle above it.

It has little to no connection to the Reformation... but if you'll visit Wittenberg, spend about 2-3 hours checking out the nearby Dessau-Wörlitz Garden Realm, a UNESCO World Heiritage site that surprisingly gets almost no mention in most English-language guidebooks. The village of Wörlitz is also quite pleasent, although mostly just a place to grab a meal and/or drink while exploring the gardens. The local specialty is freshly smoked trout... absolutely delicious. Unless you're a huge fan of Bauhaus architecture, Dessau is skippable.

Thanks to everyone one who has helped.

No one has mentioned Worms. Well worth a stop if you are heading in that direction. One has the Luther connection, as well as a beautiful, old cathedral and a lot of Jewish sites. The mikvah here is interesting to see and the Holy Sands cemetery is the oldest Jewish cemetery in Germany.