Nuremburg to Prague bus

It looks to me like a scheduling issue in that they simply have not loaded the bus schedule into the computer past October 8.
There are other bus companies that do this run, like Flixbus, Student Agency, and others.

Edit-This site shows only a couple of DB buses on Oct 13, but lots of Flixbus and Euroline buses.
https://www.busliniensuche.de/suche/?From=N%C3%BCrnberg&To=Prag&When=2017-10-13&WhenReturn=&Passengers=1&ShowRidesharing=true&ShowRidesharing=false

We saw this in the spring, too, with DB not posting bus schedules for that route terribly early. I assume they have something to re-negotiate or review so I'd check again a couple of weeks.

I'm not sure what this means, but if you try Nürnberg to Praque one week earlier, Oct 6, it shows the bus. If you click on "details", at the bottom of the details it says "runs not every day, 20. Jul until 8. Oct 2017 ". Does that mean they just haven't loaded the schedule yet, or that it doesn't run in the winter, after Oct 8.?

I also see that the similar bus from Munich to Prague does run on Oct 13. In fact, it says the Munich-Prague bus runs (but not every day) until Dec 9, when the new schedule will start.

Lee quotes what the rest of us have seen, which is what it will say when they haven't confirmed the schedule. Really no way to know what they'll do until they do it. But the buses did run all last winter and similar schedule-preview issues this spring did sort themselves out.

The DB FAQ suggests that fall timetables for that bus will be available soon. Apparently, there was a similar problem in spring - it appears that (czech?) licences are to be renewed periodically. Anyway, if the DB bus is not available at the time you want to book it simply take another one; there is much competition (Flixbus, Student Agency, Deutsch Touring etc.).