We are visiting this area in first week of September. Flight will reach at Munich at 16:10. Prague is supposed to be our first destination. Being traveling with a toddler, I do not want to stick with bus. Unless rental car is suggested, I would not opt for train in this section.
If I assume that I can come out of Airport around 17:00, I do not see any train for Prague after that.
One option is, take train to some place towards Prague and stay overnight. Take another train early morning to Prague. Can you any feasible place, from there I can reach quick to Prague ?
From an old post, I was checking Friesing to Pilsen, but not able to find any direct connection.