Fritz, can you send a snapshot of what you’re talking about? What I’m looking at says there’s two transfer points , each with about 10 minutes or so of time to transfer.
If you can’t send a snapshot, can you tell me what website you’re looking at? Thanks!
I don't think the RS forum allows snapshots. But this link shows you everything that is on offer for June 17 for connections via Koblenz and the Mosel Valley (your preference; there are shorter connections via Saarbrücken; the last segment from s. into Luxembourg is by bus):
https://int.bahn.de/en/buchung/fahrplan/suche#sts=true&so=PRAG&zo=Luxemburg%20Bahnhof&kl=2&r=13:16:KLASSENLOS:1&soid=A%3D1%40O%3DPRAG%40X%3D14451481%40Y%3D50081926%40U%3D80%40L%3D5496001%40p%3D1776103857%40i%3DU%C3%97005496001%40&zoid=A%3D1%40O%3DLuxemburg%20Bahnhof%40X%3D6134392%40Y%3D49599717%40U%3D80%40L%3D8200100%40p%3D1776103857%40i%3DU%C3%97008200100%40&sot=ST&zot=ST&soei=5496001&zoei=8200100&hd=2026-06-17T06:00:56&hza=D&hz=%5B%5B%22A%3D1%40O%3DKoblenz%20Hbf%40X%3D7588343%40Y%3D50350928%40U%3D80%40L%3D8000206%40p%3D1776103857%40i%3DU%C3%97008019023%40%22%2C%22Koblenz%20Hbf%22%2C0%5D%5D&ar=false&s=true&d=false&vm=00,01,02,03,04,05,06,07,08,09&fm=false&bp=false&dlt=false&dltv=false
The number of transfers (at least three) is indicated to the right of the scheduled travel time; click on “details” to see the transfer time available at the respective transfer points. Repeat this search using your actual travel dates, and don't forget to select Koblenz as a stopover. For the actual booking go www.cd.cz or to Omio (if you're willing to pay the small fee).
Now, let’s limit ourselves to the two most practical connections:
(1) Prague departing at 6:31 via Dresden – Mainz – Koblenz. It has a problematic 5-minute transfer in Mainz, but by clicking on “increase transfer time”, you can extend it to half an hour and still arrive in Luxembourg at the same time (by reducing the connection time in Koblenz).
(2) Prague dep. at 7:35 a.m. via Schwandorf (where you’ll get off the train to Munich) – Nuremberg – Koblenz. The layover in Schwandorf is quite long (1 hour and 5 minutes), but you could use the time to grab lunch at one of the bakeries around the station (there are three or four of them).
Alternatively, you could take the 6:45 a.m. Flixbus to Nuremberg (arr. 10:35 a.m.) and continue your journey by train from there at 11:32 a.m. That way, you’d arrive at your destination 90 minutes earlier.
Please let us know your exact travel dates so we can provide you with more detailed information (and I’m also curious to know where you managed to find a connection with only two transfers).