Help with itinerary please

Hi,

I need advice for:
1. Recommended itinerary between Rudesheim, Rhine Valley to Munich.
In the meantime, I am planning to stop over Rothenburg ODT and surroundings but still open to any input. I am looking for an original, cultural towns and scenery spots (touristy or not is OK but pls let me know if it's a touristy spot so I could prepare for the crowd). I'd skip the Black Forest and Baden2 though. If your advice is still to visit Rothenburg ODT, please also suggest any other towns and scenery spots that could be passed along on the way to Munich. I have 2 days in between Rudesheim, Rhine Valley to Munich

1. Recommended driving route (aside the Romantic Road) from Rudesheim, Rhine Valley to Rothenburg ODT or if you recommend other itinerary than Rothenburg ODT from point 1 above as long as it's on the way to Munich.
   I'm looking for a scenic route if possible.

2. Suggestion on Southern Bavaria and Western Tyrol area.
   At the moment I plan to visit Neuschwanstein, Alpsee and Fussen

3. Eagle's Nest or Alpen National Park Berchtesgaden for scenery?

4. Could I combine daytrip between the Eagle's Nest / Berchtesgaden and Salzburg, Austria?

Thanks All for any input. I really appreciate it