I think the first answer was right. Perhaps I could spend a day or so between stops. How about
Paris to Dijon 163 MI
Dijon to Geneva 170 miles
Geneva to Avignon or Mimes or Montpellier 210 miles
Montpellier to Provence 40 miles
Provence to Marseille 32 miles
I'm into museums, historic sites, wineries, etc. but not necessarily "touristy" stuff. How about Fontaineblu, Fontenay Abbey, Château de Châteauneuf, The Owl of Dijon, Museum of Fine Arts Dijon, Hôtel-Dieu Museum - Hospices de Beaune, Abbaye de Cluny, Royal Monastery of Brou, La Basilique Notre Dame de Fourvière, Musée des Confluences, Couriot - Musée de la Mine, Palais Idéal, Château de Grignan, Carrières de Lumières, Château des Baux-de-Provence...and I haven't even started on Geneva!