These distances are longer than you might think, if you're just eye-balling a small map.
Specifically what you want to understand is where the wine areas are located, in relation to your route. Because the wine areas aren't all along the route, they're in specific areas.
If you provide more specifics of what kind of wine areas you're looking for, I could probably be more specific in my recommendations.
There's also some things I could tell you about how to do a wine-tasting in France. It's not quite the informal, easy kind of thing that it is in Napa Valley or Willamette Valley. Send me a PM if you'd like to.