Itinerary Check for 2 weeks in France in early October

After Cote d'Azure, there seems to be a lot of one night stays. I think most of your vacation will be spent in a car/train/bus...i would take out a couple destinations and save them for next time :)

I'd suggest just visiting Annecy as a stop on the driving day to Colmar and add that night to any of the other destinations. Or you could stop in Annecy the night before Chamonix, to cut that driving time slightly.

I agree with Laura. I suspect I'll never understand the fascination so many Americans have with Annecy. Spend a few hours there and move on -- that's all it's woth. But definitely go to Chamonix and stay overnight so you can ride the téléphérique up to Aiguille du Midi early in the morning. If you have the time, go on to Helbronner in Italy. It's worth the time.

The weather is pretty good in October, but unpredictable in the mountains.

Think about how you will feel if the weather is bad the one day you have for Chamonix,

All that driving for wet and fog.

I think you need a little more slack in this itinerary.

I have not been to Chamonix, Annency or Reims so I cannot speak to that portion. You are seeing a good number of places and have at least 2 nights in most places; so like a Rick Steves tour, it might work. The one night stays are a concern, but I do not know the distance between them; it may be tiring to do one night stays as you need to orient yourself to the place in addition to finding the hotel, etc. The one night stays can be quite tiring for you. On tours I have been on, it is quite tiring to stay only one night and we would have a guide to orient us to the town and lead us to the hotel!

You have 4 days in the cote d'Azur, but you will not have the first day really, as you will be arriving after a long travel day. There is so much to see i that area that I would encourage you to stay longer or return on another visit. I usually stay in Villefranche sur Mer, which is 5 km outside of Nice and a smaller place but i love it.

Just my 2 cents worth. Enjoy France!

I could do this by myself, but I never plan more than four hours of transportation on a travel day. The seven hour drive to Chamonix is a long haul, especially when you add in the actual driving time, meals, getting going in the AM and getting parked and to your hotel. I wouldn't add Annecy that day, but I agree with stopping, for a look around only, after you leave Chamonix.

I hope you aren't dragging someone along. They are likely to hate you by the end of the trip. Stringing together one night stays with lots of travel ends up feeling more like a death march than a vacation. Drop either Reims or Epernay, you probably don't need both.

When you're ready to leave Amboise for Paris, drop your car and train. One less drive and much less hassle getting into Paris. Don't get a car until you are ready to drive to Chamonix, at least the last day. You can get around the coast by local train easier than driving. The only time you would need a car is to go up on the hills.

Travel is obviously highly personal, but as others have noted, there is A LOT of moving around/1 night stays and this itinerary feels very "check the box" tourism versus settling in and enjoying the rhythm of the region(s) you are in.

My thought about Reims/Epernay: I assume you are planning on visiting Champagne houses here. I don't think it would be wise to try and do both towns in 1 day...you could easily do 1 day in each which allows time for touring/tasting/eating/relaxing. Also assuming that you are "partaking" how much travel across the region is safely feasible.

You are in 7 hotels in 16 days. Since the Loire Valley is the outlier, giving you only 1.5 days but a lot of driving, you should drop it and add the time to your other stops.

I agree with Bets. Save the Loire for another trip.