Is the cost the same? If you aren't flying into Nice right before you pick up the car, it seems it would be easier to pick up the car at the rail station in Nice. Presumably you will be stopping between Nice and Avignon, hence the need for the car?
The airport pick-up is ~$100 cheaper - so not a huge deal. And yes, we will be spending 4 nights in a small home outside of Gordes that has a parking space.
I've never driven in France before either so honestly whichever location has the easiest roads to navigate, I probably would want to go with that. I noticed that the airport is on our route to Gordes so that's why I thought it may have an advantage even if it is further out than the train station. Speaking of route, I wonder if anyone has opinions on a scenic, somewhat meandering route from Nice to Gordes. We would certainly like to prioritize the scenic route!
Thanks for your reply.