Be aware if you rent a car at the train station that there's a specific, preferred way to return the car when it's time. At Avis, they have an elaborate procedure on a sheet of paper they give you (of course it's in French), so have the agent explain it to you. As I understood it, instead of telling your GPS to just take you back to the train station, you have to input a specific nearby street name and then enter the parking structure using a specific lane and then enter the rental car return area by a specific gate by punching in a code. Whew. We did it but there were some tense moments. If your agency doesn't have such a sheet, ask them explicitly what you need to do (I think I saw offices for Sixt and Enterprise in the station).
Speaking of GPS, we rented a Tomtom along with our Avis car, the guy set it up to speak English (the British way) and it was priceless. It would have been much harder to get to Pommard to start Rick's driving tour without it, and it would have been impossible to get home from Beaune to our hotel out in the sticks that night without our little friend Tim telling us the way and reassuring us that in spite of the mountain we were climbing in dense fog and darkness that we were really only 8 miles from home.