All great advice above. I drove in Provence this year and found it not only easy but fun! French drivers do like to go fast and will get right up on your tail if you're going the speed limit but don't let that intimidate you or make you feel like you have to go over the speed limit. They will pass you the second they have an opportunity. And definitely look out for the signs warning you that there are speed cameras coming up. You don't want to return home to an expensive speeding ticket. Always go the speed limits, which are pretty clearly marked.
A GPS is invaluable, I couldn't imagine not having one there. It's pretty hard to get lost with one but sometimes the GPS will recognize a roundabout turnoff that's not an actual road so my lady would say "Take the fifth exit off the roundabout" and there was no fifth exit. That's why it always helps to at least have a rough idea of your route before you leave and know the direction off the roundabout you need to go. But it is a fun, easy and beautiful place to drive. Have a great time!