Alsace Region

We spent two nights in Colmar in August and loved it. We stayed in an apartment at Reflets sur la Lauch in Petite Venise I would highly recommend it. You have a direct view across the canal to the most picturesque houses in Petite Venise.

https://www.booking.com/hotel/fr/reflets-sur-la-lauch.en-gb.html?aid=356980;label=gog235jc-hotel-XX-fr-refletsNsurNlaNlauch-unspec-us_wa-tab-L%3Aen-O%3AosSx-B%3Asafari-N%3AXX-S%3Abo-U%3AXX-H%3As;sid=cd6f33fe681114fc39e6154bfbfa92ac;dist=0&keep_landing=1&sb_price_type=total&type=total&

You can book it on booking.com, Airbnb, or other sites.

Lola thanks for your reply but they were booked

Probably Colmar or Strasbourg, they're big enough to have lodging and dining options open year round. It's likely to be chilly in November. Some wineries will likely be available with a reservation, most will probably be closed. They don't really have wineries like the US, with open public tasting rooms and regular hours. Most of the wine tasting I saw (as someone who rarely makes reservations for anything) were shops in the small towns that sold wine to the tourist crowd.

The best Alsatian wine IMO is the Gewurztraminer.

We've stayed in Alsace several times, and once was around your time frame; it was early December for a week in Dambach la Ville, a medium-sized town. There were 4 or 5 restaurants in town, but at that time of year they were rotating, so usually only 1 was open each day. But there were many wineries open, and in all of them you could just walk in for a tasting. We've stayed in Strasbourg several times, always at Hotel Gutenberg. We loved the hotel for its charm, but I noticed on their web site that they underwent a facelift a few years ago, and it looks more modern than charming. We also spent a week in Riquewihr, which is a little touristy, but beautiful, and is centrally located for wineries and wine villages. And because it's "touristy," there are a lot of hotels (we stayed in a gite), and probably open restaurants at that tie of year. But as far as things being open, the bigger cities of Colmar and Strasbourg might be your best bet.