I would rent a drive- it- yourself barge for a week. We rented from Locaboat (although there are other companies and other routes to explore). We picked up the boat in Agen, went down the Garonne Canal to the River Baise. And then back to Agen.
I think it would be an incredible experience for kids the age of yours. It gives you a week without hotels or logistical concerns. You would stock up on food but also plan to eat in little towns along the way. We awoke in the morning with a mist rising from the river — and complete silence, except for the occasional ducks quacking outside because they know boats bring bread.
Our trip had dozens (80?) locks to navigate. The boat went so slowly that the kids could get off and run or bike between locks (most places you can rent bikes with the boat). We did this on the third week of a four week trip and it remains one of our best travel experiences ever.
If you do this, be aware that boat descriptions can be over enthusiastic. A boat that sleeps 4 might have 2 of them on kitchen benches. So look at diagrams carefully and I’d recommend sizing up a bit. You need space for luggage as well as sleeping. Ours was supposed to sleep six and it was just fine for two of us.