Transportation options from airport to hotel ?? Flight arriving late

Look at https://tfl.gov.uk/JourneyPlanner
If you want to save money, take the Picadiily line to Green Park, then the Bakerloo line to Waterloo station. Goes at least every 10 minutes until well after 2 am and costs just 3.10 GBP. It takes about 70 minutes, and you still have 1/4 mile walk to the Hampton Inn.

There are quicker ways using the Heathrow Express and the Bakerloo line, but more expensive and only saving 20 minutes.

Thank you! Much appreciated

Personally I would take the Heathrow Express to Paddington and then just take a taxi from the queue upstairs. If you are at least 30 days out from flying the price for the Express is only about 8 or 9 pounds. A taxi over to the waterloo area will be about 15 - 18 pounds. That late at night I would just want to get to my hotel with as little hassle as possible, especially with luggage. You won't get into central London until nearly midnight and I can't imagine taking the tube into town that late and then having to walk to the hotel. I might even consider a taxi or car service directly from Heathrow. I really dislike taking the tube from Heathrow...it stops many times along the way and that late you'll need to get to sleep so the next day isn't a total jet-lagged loss!

I'd take the tube, as suggested above - but I don't consider 10PM on a Saturday night "really late", have no problem changing trains, carrying my luggage short distances, etc., and generally try to save money when it comes to this sort of basic transportation.

Some might prefer to take a taxi from the airport in your situation - I totally understand that - but of course it will cost many times as much.

So it comes down to what you're comfortable with, how much you want to spend, etc.

but I don't consider 10PM on a Saturday night "really late"

10PM is when the plane is scheduled to land. By the time one goes through all the arrival formalities it is getting late after a day of travel

A 30 day advance ticket on Heathrow Express is $11.20 for a weekend date. Appears last departure from LHR is 1130PM.
I would be looking at taking the HEX, if I had to do it.

Awesome! Blackberry cars quoted me 49 pounds..

I would investigate the cost to take taxi from Paddington to hotel after using Heathrow Express from airport to Paddington. This avoids possibly having to haul luggage up steps at Tube stations.

As it is a Saturday night the underground runs all the way through it, so there is no risk of being too late.

Route on the Night Tube is Heathrow Terminals 5/3,2 to Piccadilly Line to Green Park, Jubilee Line to Waterloo. Service every ten minutes or so. The Bakerloo Line doesn't run through the night.

Cost £3.10 as above.

Take the car service. While it's not a difficult trip by tube and then about a five minute walk after getting out of Waterloo....at that hour, and after a long international flight, take the car service. It will make your life easier.

Awesome! Blackberry cars quoted me 49 pounds..

For me, that would be £49 well spent. After a long day travelling and at that hour the last thing I want to be doing is faffing about with public transport and walking. Airport straight to hotel, straight to bed and refreshed in the morning. Landing at 10pm could potentially see you leaving the airport closer to midnight if things aren't in your favour.

Have you guys used blackberry cars before?

Yes, I’ve used Blackberry for years for transport to Heathrow, most recently last September. Well maintained vehicles, good drivers, responsive customer service, and excellent price. Highly recommend.

Thank you to everyone!