Laura and geovagriffith both mentioned visiting ancestral locations.
My husband and I have found this to be a very satisfying way to plan a vacation---or at least part of one. It's a wonderful way to bring obscure locations to life. We have visited my husband's ancestral locations in Germany and Ukraine (brought a 2nd cousin, twice removed back to attend high school for a year), and last year he and our 3 adult kids reclaimed Luxembourg citizenship through a gggrandfather. Last summer we returned to the German villages (and Luxembourg) with our kids.
In 2018 we spent 3 weeks primarily visiting my ancestral locations in Cambridgeshire, Essex, and Suffolk. (In addition, my grandmother was born in Walthomstowe, which has an lovely William Morris Gallery https://wmgallery.org.uk/?gmb
The little, off the radar villages were delightful as well as meaningful. (Helpston, Cambridgeshire has ancestral significance for me, but now I see that Trip Advisor names it one of the best places to visit, 2023. I had not heard of it until I learned of my family history) When it's just the my husband and I travelling, we always have a reservation for the last night before flying home as well as a few other key locations along the way. We leave parts of the trip as flexible as possible. This worked particularly well in Suffolk when I made a FB connection with a village historian the morning after our visit to my gggrandfather's village, Stradbroke. We had spent the night in a nearby village, ready to leave the area the next day. We were discouraged that we hadn't made any discoveries in the graveyard nor the records office (in a larger town).
Because we had a couple of days before our scheduled reservation in Cambridgeshire, we ended up returning to the village to meet the woman whose late husband had been the village archivist.. We met with the woman in the graveyard which we'd visited the day before. (The lighting was different and we spotted at least one tombstone with the family name.) It turned out that she had a copy of the petition my ggggrandfather and 29? others had signed requesting $ from the parish so they could immigrate to Canada. The parish was happy to shed the financial burden of these poor families. We learned they'd set sail from Great Yarmouth. After a visit in the woman's home to see the document, we headed out of town to wander through a few villages to eventually find accommodation for the night. We came to a T in the road. One arrow pointed to "Great Yarmouth." My husband and I looked at each other and said, "Let's go!". We pulled into a nearby lot, looked at the map, reset the satnav and off we went. It was amazing to think that the statue of Nelson I saw by sea was probably the last thing my ggggrandparents (and my young gggrandfather) saw as they left.
(Sorry, I get carried away once I get sharing about the serendiptous events on our trips.)
My heritage is mostly British/Irish, so I can insert an ancestral location into almost any trip in the UK. This fall we will travel to Scotland with our daughter and her partner. He has an ancestral connection to Scotland, and we're eager to see some new sights there as well. My husband and I will have about 4 extra days in which we will visit the Dumfries and Galloway area which I've recently discovered was the birthplace of another gggrandmother and her maternal line. Walking the streets and visiting the churches as my ancestor would have done touches my soul in ways that no museum exhibit does.