Hotel rec for Prague 2 or Prague 7

I would suggest staying in Prague 3. We stayed in an Airbnb there -- the train station was a 15 minute walk or very short tram ride away.

Prague 7 is good as is Prague 6, but the whole of Prague has fantastic and very cheap transport links it is quite easy to stay in most areas. I have stayed in Prague 6 numerous times lots of decent places to stay , I am in Prague tomorrow staying in Clarion Hotel near I P Pavlova metro right in the middle of Prague 2 area, this is a very popular area and has numerous hotels of all grades, superb transport links to all parts of the city, train station, Wenselas square all easily walkable.it is not a major tourist area but there will be a lot of tourists in the area because of the number of hotels.
I don't know what method you are using to book but I often book through Booking.com where I have the option for paying for non refundable rooms or paying a higher fee where i can get a refund.

In Prague 7 look for Mama Shelter. Great place for meeting people if you are solo and very well connected to get into the centre of town.

I would use google street view and take a look at the possibilities.

Thanks for the replies everyone.

@Jason - Mama Shelter has come up before during my research. The location is good and the hotel is very well rated but I have to admit it does seem a bit too "quirky" for my tastes.

@UncleGus - I never really considered Prague 6, but I'll give it a closer look. Thanks for the recommendation.

I use Booking.com as well, in conjunction with the RS and Lonely Planet (pre-2023) books for ideas, but then usually end up booking direct with the hotel unless I have a very good reason to go with Booking. In my experience, cancellation policy is usually fairly consistent across platforms since it is determined by the hotel. I was confused about Hotel Anna because I don't recall ever seeing a hotel with no flexible rates available anywhere.

I'm still leaning toward Vinohrady, but I'll keep looking in Prague 6 and 7 as well.

I got curious and looked around the neighborhood of the Hotel Anna. Very nice indeed. At 20 to 40 minutes to old town (walk vs public), its a bit far out for my taste, but you know the neighborhood is so nice maybe I changed my thinking. So I looked at the prices. Also very nice. Then the issue of pre-pay no refund. They have a little game going on. That appears to be based on some combination of how far in advance and for how long. A short stay, 3 or 4 nights they will quote you refundable in through mid May, longer stays stop the offer in March. I get the reasons why, but gives me a bad taste, so I would pass on that alone.

@Mr É - I agree, it gives me a bad taste too. I will be avoiding them unless they change their flexible rate availability.