Can anyone recommend a tour guide for an approximate 10 day tour of the Czech Republic?
Actual tour guides are not so typical as the infrastructure system with bus and trains is very friendly. Most people take day trips from Prague or 1 or 2- night stays elsewhere.
When do you plan to visit?
Some possible options for you.
https://www.tripadvisor.com/Attractions-g274707-Activities-c42-t288-Prague_Bohemia.html