Just wanted to correct you, where you say upthread "I know it's tough to get to this place...".
It is not tough to get to Guam at all, especially if you live in San Francisco or other large cities on the west coast (it's actually a lot easier to get to Guam than to reach many places in the USA). You can fly there with just one stop (via Tokyo, Seoul, and multiple other Asian cities) on large jets with familiar airlines. For you it would be just one stop on United or Delta, perhaps other major airlines.
I didn't spend any time in Guam, but did connect through there, coming from Palau and heading for Japan. My impression was that Guam's airport felt like a bit like an airport in Hawaii. Very much mainstream American, though with a slight "island vibe" and an Asian/Pacific flavor. Not really exotic, not edgy, not difficult, in any way. Admittedly, I never got beyond the airport, but did do some research on Guam (coming from Palau, I had to go through Guam to get to Tokyo, and was thinking about trying to extend my layover there, but ultimately decided not to). It has been an American possession and has had a huge US military presence since WWII, and that has had a profound influence on life there - you should find familiar chain stores and all the brands you know from home, it would feel a lot like going to Florida or the US Virgin Islands (especially so, since there's historic ties to Spain, the previous colonial power).
While many people might still picture the islands in this region of the Pacific as very exotic, alien places, untouched by civilization, that is, I think, an outdated notion and far from what you will find there. Connections to the US (and major Asian nations) are longstanding, deep-rooted and impossible to miss. The rise of Chinese tourism (especially in recent years) and longstanding tourism from Japan, have transformed these islands from the sleepy backwaters many people think they still are. They are not!
You can still find pretty beaches, clear water and abundant sunshine. But you will also find a lot of development (and all the environmental problems that brings) and plenty of foreign tourists. When I was in Palau a few years ago, I was amazed at the large numbers of Chinese tourists (and I understand Chinese tourism to these islands has continued to expand very very rapidly, although admittedly curtailed right now due to the corona virus). These places are heavily marketed in China, Japan and elsewhere in Asia, and tourists come in large numbers. And Guam is part of the USA - has been for a long time.
Anyway, if you are going to Guam or other islands in the region expecting to find an untouched paradise, I would urge you to calibrate your expectations carefully. If, for example, you want to be the lone person on a perfect beach, or you want to find someplace without a 7-11, without everyone with their heads face-down in their iPhones, without Micky D's and many other trappings of a generic, homogenized town in America, you are going to have to work harder and go much further than Guam or any of the islands with commercial air service. There are few such places left in the world, and getting to them takes a lot of time and effort. Doesn't mean you won't enjoy being in these islands, but you won't exactly feel like Robinson Crusoe (or Tom Hanks in Cast Away).