Chile is a huge country so you may want to look for a guide for the part you’re going to visit. When I went to Santiago for a week in 2014 I just used TripAdvisor to look up places to see in the city. While there we took a bus over to Valparaiso. For the limited amount of time we were there, a guide wasn’t really needed. There is only limited train service, i.e., it only runs either north or south from Santiago (I can’t remember), so travel outside the city will probably be by bus. While there we stayed at hotel Plaza San Francisco. Great hotel and staff, and a good location for seeing the sights in Santiago. The main bus terminal was about a mile from it on the same main road; Libertador Bernardo O’Higgins.