+1 for Nigel. I suggest you sleep in Antwerp and see Brussels only if the art museums there are important to you. I put Bruges ahead of Gent, but the Mystic Lamb is pretty important and a 7 day a week attraction.
Regarding your husband's preference, I cannot say enough good things about Antwerp. It has much more than you can see in three days, and a wide variety of things to do. It has many medieval corners, as well as more modern streets. It's a wonderful place for walking. Pre-covid, it also had a wide variety of affordable restaurants. The most important art museum in Antwerp is still closed for its gut renovation. This board always produces a variety of "favorite" cities in this area.
Edit: I also chased down the female "pis" statue, placed by the local restauranteurs ... . It's the least significant piece of art in the entire city, alas. Kiki Smith has a real sculpture ("untitled") with a similar ... er ... theme ... at The Grounds for Sculpture in central New Jersey.
The walk, bus, or subway to the train station is worth considering when selecting a hotel. I have waited in lines at the Antwerp station. The historic centers of Bruges and Gent and Antwerp are a looong walk from the rail stations, but I have walked them all. Note that Brussels has a different public transit agency (and stored value card) than the other cities do. But (last time I was there) the other cities all used the SAME card.