I stayed a couple of nights in the Motel One in Brussels and can definitely recommend it.
Obviously it’s a chain hotel, but I do like the Motel One chain - small rooms, but air conditioned and very comfortable, nice and stylish with a good continental breakfast.
I particularly like the location of this hotel. It’s on Rue Royale, which is a very short (uphill) walk from Brussels Central station. It’s walkable both to the historic centre around Grand Place and also the museums and palaces around Place de Palais and Place Royale.
Also there is a really nice bar and a courtyard where you can sit outside with a drink.
It felt nice to get away from the crowds of tourists around Grand Place and surrounding streets. At first glance there didn’t seem to be many restaurants around the hotel but then I discovered loads around the nearby Place de La Liberte and the roads going off in all directions.